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基因名: | Low-density lipoprotein receptor-related protein 6, LRP6 |
别名: | LDL receptor-related protein 6, ADCAD2, STHAG7 |
描述: |
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined. |
基因ID: |
4040 |
规格: |
1× 10^6 |
细胞形态: | 上皮样, 贴壁细胞 |
传代比例: | 1:3~1:6 |
培养体系: |
90% DMEM+10% FBS |
冻存液体系: |
50% DMEM+40% FBS+10% DMSO |
文档: |
说明书 |