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基因名: | actinin alpha 1, ACTN1 |
别名: | BDPLT15 |
描述: | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. |
基因ID: | 87 |
规格: | 1× 10^6 |
细胞形态: | 上皮样, 贴壁细胞 |
传代比例: | 1:3~1:6 |
培养体系: | 90% DMEM+10% FBS |
冻存液体系: | 50% DMEM+40% FBS+10% DMSO |
文档: | 说明书 |