Purified Anti-Human CD8a Antibody (25 μg)

目录号 FD0003
库存状态有库存

¥1,090.00

数量

Reactivity:	Human
Applications:	FCM
Host Species:	Mouse
Isotype:	Mouse IgG2a, κ
Clonality:	Monoclonal
Conjugation:	Unconjugated
Synonyms:	T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL
Background:	CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Gene ID:	925
SwissProt:	P01732
Concentration:	0.5 mg/mL
Buffer:	PBS with 0.05% Proclin300
Storage:	Store at 2~8°C. Do not freeze.
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