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基因名: | ubiquitin protein ligase E3 component n-recognin 1, UBR1 |
别名: | JBS |
描述: |
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. |
基因ID: |
197131 |
规格: |
1× 10^6 |
细胞形态: | 上皮样, 贴壁细胞 |
传代比例: | 1:3~1:6 |
培养体系: |
90% DMEM+10% FBS |
冻存液体系: |
50% DMEM+40% FBS+10% DMSO |
文档: |
说明书 |